Nicotinamide riboside is a vitamin B3 variation that has recently gained much attention because of its potential health benefits. NR is commonly marketed as an anti-aging substance and can be found in several products with that purpose. However, this vitamin B3 alternative may have other benefits yet to be explored.  

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Even though research about nicotinamide riboside is ongoing, several studies indicate multiple associated benefits. Still, you should take these benefits with a grain of salt as more research is necessary to confirm the effects and their actual scope. In this highly digitalized and dynamic world, information is crucial.  

People are always looking for new, safe, and reliable ways to deal with health issues. However, only some things are genuine and offer real benefits. Today, we’ll talk about the benefits you get from using NR.  

1. It helps activate healthy aging enzymes  

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Nicotinamide riboside increases the levels of NAD+ within the body. NAD+ is a coenzyme crucial for various biological reactions and optimal health. However, NAD+ levels naturally decline as we age and are linked with various diseases.  

Nicotinamide riboside is the building block for NAD+ and increases its levels. Having more NAD+ enzymes also help with aging. NAD+ activates other enzymes like sirtuins, positively affecting animals’ overall health and lifespan. Studies show that sirtuins can repair damaged DNA, reduce inflammation, and improve stress resistance, contributing to healthy aging.  

Sirtuins are known for their lifespan-extending effects linked with calorie restriction. Other enzymes activated by NAD+ are PARPs and ADP-ribose, which can repair DNA. Increased PARP activity also contributes to a longer lifespan.  

2. May reduce heart disease causes  

The older we are, the higher the chances are of heart disease. Heart disease is still the leading cause of death in the world, and it’s a significant health issue. Our blood vessels become less flexible, stiffer, and thicker as we age, especially in blood vessels like the aorta.  

These changes raise blood pressure over time, putting a lot of stress on the heart and making the organ work harder. Studies show that increasing NAD+ levels helped animals reverse the aging changes related to arteries and, subsequently, reduce the chances of heart diseases.  

On the other hand, studies with humans have shown that nicotinamide riboside helps raise NAD+ levels, which reduces blood vessel stiffness and helps reduce systolic blood pressure in adults at risk of high blood pressure.  

3. It may improve brain health  

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Since NAD+ declines naturally over the years, the neurons lose the capacity to resist stress and function normally. That leads to various neurodegenerative issues. Since NR is a powerful NAD+ precursor, it can replenish the NAD+ levels, which could lead to various neurological benefits.  

NAD+ increase can boost brain cell energy metabolism, help prevent degeneration, and boost stress resistance. NR also helps support cognitive function by helping energy production and cellular health within brain cells. Some preliminary research indicates that NR can improve learning and memory abilities. 

Diminished brain function is another symptom of lowered NAD+ levels, and taking NR helps you get your levels up to support healthy brain functions and reduce the symptoms of aging.  

4. It can help increase the metabolic rate  

Like with most of its other benefits, NR might be able to help with metabolism issues because of its effects on elevating NAD+ levels in the body. NAD plays a vital role in converting food into energy. That means it’s an essential element of metabolism regulation.  

As people age, their metabolic efficiency decreases, leading to weight gain and difficulty losing weight. By increasing NAD+ with NR, people can improve their metabolic function, which helps with weight management and efficient energy use. The fact that NR supplementation might contribute to sirtuin activation also helps regulate metabolism.  

This protein group directly affects metabolism and cellular health. All these effects improve metabolic function, but it’s important to mention that this isn’t a magic fix for weight loss.  

5. Improves cellular health

NAD+ plays a big part in energy production and cellular metabolism. It’s a linchpin molecule that puts together cellular health and diet. It helps transfer the energy from the food that we ingest into cells so that it can be used for performing various functions. Since our NAD+ levels drop as we age, our cellular energy production also drops.  

NR can increase the NAD+ levels and reverse the aging effects on cellular health. Simply put, NR can improve both metabolic rate and energy metabolism at a cellular level. It helps cells resist stress, repair themselves more effectively, and function optimally.  

NR has even been linked with preventing the development of major illnesses like Diabetes, hearing loss, Parkinson’s, ALS, and Alzheimer’s. Even though traces of NR can be found in various foods, the only real benefits are achieved through supplementation.  


Even though Nicotinamide riboside shows great promise and encouraging studies, more research is required to confirm the exact benefits concerning dosage and frequency of use. However, NR is already available in the form of capsules and tablets at health-food stores, and there are no significant side effects you should be worried about.  

And finally, make sure to remember to visit your doctor for a final consultation. They are experts in the field who can help you understand everything in the clearest possible way.